SCHEMBL30953034

SCHEMBL30953034

CC(C)(C)OC[C@@H](NC(=O)OCc1ccccc1)C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 9/20 0.40
▸ CTSS P25774 5/20 0.40
▸ CTSK P43235 4/20 0.40
▸ CTSB P07858 4/20 0.37
▸ ITGB3 P05106 2/20 0.36
▸ ITGAV P06756 2/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ ANPEP P15144 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953422 0.86 CTSL (0.37) CTSLCTSSCTSKCTSBITGB3
SCHEMBL30953350 0.86 CTSL (0.37) CTSLCTSSCTSKCTSBITGB3
SCHEMBL30953265 0.86 CTSL (0.37) CTSLCTSSCTSKCTSBITGB3
SCHEMBL30953412 0.85 IGF1R (0.38) CTSS
SCHEMBL30953414 0.85 IGF1R (0.38) CTSS
SCHEMBL30953154 0.84 CTSL (0.34) CTSLCTSSCTSKCTSBITGB3
SCHEMBL30953083 0.83 IL17A (0.34) CTSL
SCHEMBL30953369 0.82 IGF1R (0.35) —
SCHEMBL30953159 0.82 IL17A (0.40) CTSLCTSKCTSBANPEP
SCHEMBL30953130 0.80 IL17A (0.48) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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