SCHEMBL30953083

SCHEMBL30953083

Cn1nccc1C(=O)NC(COC(C)(C)C)C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 4/20 0.34
▸ CDK2 P24941 2/20 0.31
▸ IGF1R P08069 1/20 0.31
▸ CCNE1 P24864 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ TAS1R3 Q7RTX0 1/20 0.31
▸ TAS1R1 Q7RTX1 1/20 0.31
▸ TAS1R2 Q8TE23 1/20 0.31
▸ MAPK14 Q16539 2/20 0.30
▸ PSEN1 P49768 1/20 0.30
▸ PSEN2 P49810 1/20 0.30
▸ APH1B Q8WW43 1/20 0.30
▸ NCSTN Q92542 1/20 0.30
▸ APH1A Q96BI3 1/20 0.30
▸ PSENEN Q9NZ42 1/20 0.30
▸ MAPK13 O15264 1/20 0.30
▸ BUB1 O43683 1/20 0.30
▸ SCN10A Q9Y5Y9 1/20 0.30
▸ CTSL P07711 1/20 0.30
▸ MGAT2 Q10469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953308 0.94 IL17A (0.33) IL17ACDK2CCNE1GSK3B
SCHEMBL30953017 0.86 IL17A (0.36) IL17ACDK2IGF1RCCNE1GSK3B
SCHEMBL30953130 0.84 IL17A (0.48) IL17AMAPK14
SCHEMBL30952940 0.84 IL17A (0.39) IL17ACDK2CCNE1GSK3BTAS1R3
SCHEMBL30952976 0.83 IL17A (0.36) IL17ACDK2CCNE1GSK3BMAPK14
SCHEMBL30953034 0.83 CTSL (0.40) CTSL
SCHEMBL30953369 0.82 IGF1R (0.35) IL17AIGF1RMAPK14MAPK13
SCHEMBL30953414 0.82 IGF1R (0.38) IGF1RSCN10A
SCHEMBL30953412 0.82 IGF1R (0.38) IGF1RSCN10A
SCHEMBL30952938 0.82 IL17A (0.45) IL17ACDK2CCNE1GSK3BBUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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