SCHEMBL30953080

SCHEMBL30953080

Cc1cc(COC(=O)N[C@H](C(=O)Nc2cc(CN3C[C@@H](C(F)(F)F)NC3=O)ccn2)C2CCC(F)(F)CC2)no1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.41
▸ TRPA1 O75762 4/20 0.32
▸ ABCB11 O95342 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ SLCO1B1 Q9Y6L6 1/20 0.31
▸ MAPK1 P28482 1/20 0.30
▸ CYP3A4 P08684 2/20 0.30
▸ TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953029 0.89 IL17A (0.38) IL17AABCB11CHRM2SLCO1B1CYP3A4
SCHEMBL30953159 0.88 IL17A (0.40) IL17AMAPK1
SCHEMBL30952974 0.86 IL17A (0.42) IL17AABCB11CHRM2SLCO1B1MAPK1
SCHEMBL30952938 0.81 IL17A (0.45) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953013 0.81 IL17A (0.46) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953154 0.81 CTSL (0.34) —
SCHEMBL30953030 0.81 IL17A (0.47) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953047 0.80 IL17A (0.44) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953257 0.80 IL17A (0.40) IL17AMAPK1
Hydrochloric Acid SCHEMBL30953455 0.79 IL17A (0.43) IL17AABCB11CHRM2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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