SCHEMBL30953233

SCHEMBL30953233

CC(C)n1nccc1C(=O)N[C@H](C(=O)Nc1cc(C(C)(C)N2C[C@@H](C(F)(F)F)NC2=O)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 7/20 0.35
▸ MAP3K12 Q12852 3/20 0.33
▸ DLK1 P80370 2/20 0.33
▸ MAPT P10636 2/20 0.32
▸ GSK3B P49841 2/20 0.32
▸ ABCB11 O95342 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ SLCO1B1 Q9Y6L6 1/20 0.31
▸ BTK Q06187 2/20 0.30
▸ NR3C2 P08235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953419 0.92 IL17A (0.34) IL17AMAP3K12DLK1MAPTGSK3B
SCHEMBL30953344 0.91 IL17A (0.34) IL17AMAPTGSK3BABCB11CHRM2
SCHEMBL30953460 0.85 AAK1 (0.37) IL17AMAPTGSK3BABCB11CHRM2
SCHEMBL30953013 0.85 IL17A (0.46) IL17AABCB11CHRM2SLCO1B1NR3C2
SCHEMBL30953516 0.83 IL17A (0.41) IL17AABCB11CHRM2SLCO1B1BTK
SCHEMBL30953215 0.83 MAPT (0.34) IL17AMAP3K12DLK1MAPTGSK3B
SCHEMBL30953141 0.80 IL17A (0.34) IL17A
SCHEMBL30953094 0.79 IL17A (0.35) IL17ANR3C2
SCHEMBL30953104 0.79 IL17A (0.38) IL17ANR3C2
SCHEMBL30953075 0.78 IL17A (0.38) IL17AGSK3BABCB11CHRM2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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