SCHEMBL30953419

SCHEMBL30953419

Cn1nccc1C(=O)N[C@H](C(=O)Nc1cc(C(C)(C)N2C[C@@H](C(F)(F)F)NC2=O)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.34
▸ CTSS P25774 1/20 0.32
▸ CDK2 P24941 2/20 0.32
▸ GSK3B P49841 3/20 0.31
▸ MAPT P10636 2/20 0.31
▸ ABCB11 O95342 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ SLCO1B1 Q9Y6L6 1/20 0.31
▸ BUB1 O43683 1/20 0.31
▸ BTK Q06187 2/20 0.31
▸ UCHL1 P09936 1/20 0.31
▸ USP30 Q70CQ3 1/20 0.31
▸ MAP3K12 Q12852 2/20 0.30
▸ DLK1 P80370 1/20 0.30
▸ CCNE1 P24864 1/20 0.30
▸ SYK P43405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953233 0.92 IL17A (0.35) IL17AGSK3BMAPTABCB11CHRM2
SCHEMBL30953344 0.91 IL17A (0.34) IL17AGSK3BMAPTABCB11CHRM2
SCHEMBL30953460 0.86 AAK1 (0.37) IL17AGSK3BMAPTABCB11CHRM2
SCHEMBL30953075 0.85 IL17A (0.38) IL17ACTSSCDK2GSK3BABCB11
SCHEMBL30952938 0.85 IL17A (0.45) IL17ACTSSCDK2GSK3BABCB11
SCHEMBL30953011 0.84 IL17A (0.37) IL17ACTSSCDK2GSK3BABCB11
SCHEMBL30953516 0.84 IL17A (0.41) IL17AABCB11CHRM2SLCO1B1BTK
SCHEMBL30953215 0.84 MAPT (0.34) IL17AGSK3BMAPTBTKUSP30
SCHEMBL30953054 0.83 IL17A (0.40) IL17ACTSSCDK2GSK3BABCB11
SCHEMBL30953337 0.80 IL17A (0.33) IL17ACTSSCDK2GSK3BBUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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