SCHEMBL30953344

SCHEMBL30953344

CCn1nccc1C(=O)N[C@H](C(=O)Nc1cc(C(C)(C)N2C[C@@H](C(F)(F)F)NC2=O)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.34
▸ MEN1 O00255 3/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ MAPT P10636 3/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ RAB9A P51151 3/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ ABCB11 O95342 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ SLCO1B1 Q9Y6L6 1/20 0.31
▸ ABL1 P00519 1/20 0.31
▸ BTK Q06187 2/20 0.31
▸ BRAF P15056 1/20 0.30
▸ KDR P35968 1/20 0.30
▸ GSK3B P49841 1/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953419 0.91 IL17A (0.34) IL17AMAPTABCB11CHRM2SLCO1B1
SCHEMBL30953233 0.91 IL17A (0.35) IL17AMAPTABCB11CHRM2SLCO1B1
SCHEMBL30953516 0.85 IL17A (0.41) IL17AABCB11CHRM2SLCO1B1BTK
SCHEMBL30953460 0.84 AAK1 (0.37) IL17AMAPTABCB11CHRM2SLCO1B1
SCHEMBL30953215 0.82 MAPT (0.34) IL17AMAPTBTKGSK3B
SCHEMBL30952959 0.81 IL17A (0.32) IL17AMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30952924 0.80 MEN1 (0.33) IL17AMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30953056 0.78 MEN1 (0.33) IL17AMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30952938 0.78 IL17A (0.45) IL17AABCB11CHRM2SLCO1B1GSK3B
SCHEMBL30952990 0.78 IL17A (0.35) IL17AMEN1KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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