Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.45 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357498 | 0.75 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL291929 | 0.71 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL1719503 | 0.68 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL3322669 | 0.68 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL291770 | 0.68 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6395827 | 0.67 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL15876482 | 0.67 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3957428 | 0.67 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3322021 | 0.66 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL15876480 | 0.66 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234347-A1 | Substituted Pteridines substituted with a Four-Membered Heterocycle | BOEHRINGER INGELHEIM INTERNATIONL GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234347-A1 | Substituted Pteridines substituted with a Four-Membered Heterocycle | UACA, LTC4S, PMP22 | PDE4A 1509/4885PDE4B 1446/4885PDE4C 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.