SCHEMBL30953483

SCHEMBL30953483

C[C@H](OC(C)(C)C)[C@H](N)C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ IGF1R P08069 2/20 0.34
▸ IL17A Q16552 3/20 0.33
▸ AAK1 Q2M2I8 5/20 0.33
▸ CYP3A4 P08684 4/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ NR3C2 P08235 5/20 0.33
▸ MAPT P10636 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ CDK5 Q00535 1/20 0.31
▸ DYRK1A Q13627 1/20 0.31
▸ CDK5R1 Q15078 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953347 1.00 IGF1R (0.34) IGF1RIL17AAAK1CYP3A4MAPK14
SCHEMBL30953369 0.86 IGF1R (0.35) IGF1RIL17AAAK1CYP3A4MAPK14
Hydrochloric Acid SCHEMBL30953252 0.84 NR3C2 (0.37) IL17ANR3C2CDK5DYRK1ACDK5R1
SCHEMBL30953350 0.83 CTSL (0.37) —
SCHEMBL30953422 0.83 CTSL (0.37) —
SCHEMBL30953265 0.83 CTSL (0.37) —
SCHEMBL30953017 0.83 IL17A (0.36) IGF1RIL17AMAPK14GSK3B
Hydrochloric Acid SCHEMBL30953395 0.82 SLC5A1 (0.33) IGF1RIL17ANR3C2
SCHEMBL30953226 0.81 NR3C2 (0.37) IGF1RIL17AMAPK14NR3C2CDK5
Hydrochloric Acid SCHEMBL30953230 0.81 NR3C2 (0.36) IGF1RIL17AMAPK14NR3C2CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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