SCHEMBL30953017

SCHEMBL30953017

C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1ccnn1C)C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 3/20 0.36
▸ CDK2 P24941 4/20 0.33
▸ PYGL P06737 3/20 0.32
▸ CCNE1 P24864 3/20 0.32
▸ GSK3B P49841 3/20 0.32
▸ TAS1R3 Q7RTX0 1/20 0.32
▸ TAS1R1 Q7RTX1 1/20 0.32
▸ TAS1R2 Q8TE23 1/20 0.32
▸ MAPK14 Q16539 2/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ IGF1R P08069 1/20 0.31
▸ MBOAT4 Q96T53 1/20 0.30
▸ MAPK13 O15264 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953027 0.92 IL17A (0.37) IL17APYGLMAPK14IGF1R
SCHEMBL30952940 0.88 IL17A (0.39) IL17ACDK2CCNE1GSK3BTAS1R3
SCHEMBL30953083 0.86 IL17A (0.34) IL17ACDK2CCNE1GSK3BTAS1R3
SCHEMBL30953026 0.86 IL17A (0.41) IL17APYGLIGF1R
SCHEMBL30952928 0.85 IL17A (0.41) IL17APYGL
SCHEMBL30953012 0.85 IL17A (0.38) IL17APYGL
SCHEMBL30953067 0.84 IL17A (0.48) IL17APYGL
SCHEMBL30953308 0.84 IL17A (0.33) IL17ACDK2CCNE1GSK3B
SCHEMBL30953347 0.83 IGF1R (0.34) IL17AGSK3BMAPK14IGF1R
SCHEMBL30953483 0.83 IGF1R (0.34) IL17AGSK3BMAPK14IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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