SCHEMBL30953913

SCHEMBL30953913

COCCS(=O)(=O)Nc1ccc(C(=O)Nc2nccc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27457432 0.92 KIF18A (0.80) KIF18A
SCHEMBL30953921 0.89 KIF18A (0.76) KIF18A
SCHEMBL30953942 0.88 KIF18A (0.71) KIF18A
SCHEMBL27457316 0.88 KIF18A (0.72) KIF18A
SCHEMBL30953937 0.88 KIF18A (0.72) KIF18A
SCHEMBL27457431 0.87 KIF18A (0.62) KIF18A
SCHEMBL27455493 0.86 KIF18A (0.76) KIF18A
SCHEMBL27457278 0.86 KIF18A (0.76) KIF18A
SCHEMBL30953922 0.84 KIF18A (0.76) KIF18A
SCHEMBL30953950 0.84 KIF18A (0.71) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO claimed
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
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