SCHEMBL30953984

SCHEMBL30953984

Cc1cc(N2CCC(F)(F)CC2)nc(NC(=O)c2ccc(N)cc2N2CCC3(CC2)CC3)n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455410 1.00 KIF18A (0.57) KIF18A
SCHEMBL27457051 0.90 KIF18A (0.57) KIF18A
SCHEMBL30953991 0.90 KIF18A (0.57) KIF18A
SCHEMBL27457120 0.89 KIF18A (0.72) KIF18A
SCHEMBL30953936 0.89 KIF18A (0.72) KIF18A
SCHEMBL27456284 0.87 KIF18A (0.55) KIF18A
SCHEMBL27457277 0.87 KIF18A (0.53) KIF18A
SCHEMBL30954028 0.87 KIF18A (0.53) KIF18A
SCHEMBL30953953 0.86 KIF18A (0.73) KIF18A
SCHEMBL30954018 0.86 KIF18A (0.54) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
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