Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15727819 | 0.89 | HTT (0.43) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL30353758 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL15081285 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL28306231 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL9762646 | 0.80 | KMT2A (0.59) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL27484194 | 0.80 | MEN1 (0.50) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL31509456 | 0.79 | MAPK1 (0.47) | SMN1; SMN2KMT2AMEN1HTTMAPT | |
| SCHEMBL3720601 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL3720610 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMEN1HTTGAA | |
| SCHEMBL29607722 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |