Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081285 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL30353758 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL22082614 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAHTTMAPTRORC | |
| SCHEMBL28306231 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL22081952 | 0.83 | RORC (0.46) | ALDH1A1LMNAMAPTKDM4ERORC | |
| SCHEMBL6626231 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL28819003 | 0.82 | COMT (0.46) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL29607722 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL3720610 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL3722699 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |