SCHEMBL30954047

SCHEMBL30954047

COCCN1CCOc2c1cc(Cl)c(F)c2C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
GRM5 P41594 1/20 0.34
HTR4 Q13639 2/20 0.34
HTR1A P08908 1/20 0.34
ADRA2C P18825 1/20 0.34
ACHE P22303 1/20 0.34
PTGS1 P23219 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR3A P46098 1/20 0.34
KCNH2 Q12809 1/20 0.34
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NOTUM Q6P988 1/20 0.33
KAT7 O95251 1/20 0.33
KAT6A Q92794 1/20 0.33
KAT5 Q92993 1/20 0.33
KAT8 Q9H7Z6 1/20 0.33
BCL2 P10415 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27434272 1.00 TSHR (0.34) TSHRGRM5HTR4HTR1AADRA2C
SCHEMBL30954063 0.93 HTR4 (0.38) TSHRHTR4HTR1AADRA2CACHE
SCHEMBL27434199 0.93 HTR4 (0.38) TSHRHTR4HTR1AADRA2CACHE
SCHEMBL27434257 0.88 TSHR (0.38) TSHRHTR4HTR1AADRA2CACHE
SCHEMBL30954147 0.88 WDR5 (0.33) TSHRLMNASMN1; SMN2BCL2MCL1
SCHEMBL30954145 0.87 AR (0.36) TSHRHTR4HTR3ALMNAMAPT
SCHEMBL27434163 0.87 AR (0.36) TSHRHTR4HTR3ALMNAMAPT
SCHEMBL30954157 0.84 CHRM1 (0.37) TSHRLMNAMAPTSMN1; SMN2NOTUM
SCHEMBL27434015 0.84 CHRM1 (0.37) TSHRLMNAMAPTSMN1; SMN2NOTUM
SCHEMBL30954073 0.84 HSP90AA1 (0.35) TSHRHTR4LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed