SCHEMBL30954080

SCHEMBL30954080

CCOc1c(Cl)cc2c(c1C(=O)O)OCCCN2C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
TSHR P16473 1/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
DRD2 P14416 2/20 0.34
GAA P10253 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABL1 P00519 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RIN1 Q13671 1/20 0.33
PTGER4 P35408 1/20 0.33
ITGB2 P05107 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27432967 1.00 HSD17B10 (0.42) HSD17B10TSHRLMNAHTTDRD2
SCHEMBL27432956 0.89 HSD17B10 (0.40) HSD17B10TSHRLMNAMEN1KMT2A
SCHEMBL30954043 0.87 KDM4E (0.41) HSD17B10DRD2SMN1; SMN2RAB9AKMT2A
SCHEMBL27432942 0.87 KDM4E (0.41) HSD17B10DRD2SMN1; SMN2RAB9AKMT2A
SCHEMBL30954143 0.81 RORC (0.37) TSHRLMNADRD2SMN1; SMN2MEN1
SCHEMBL27433032 0.81 RORC (0.37) TSHRLMNADRD2SMN1; SMN2MEN1
SCHEMBL30954108 0.80 KDM4E (0.43) HSD17B10DRD2ALDH1A1MAPT
SCHEMBL27432464 0.80 KDM4E (0.43) HSD17B10DRD2ALDH1A1MAPT
SCHEMBL27433029 0.78 LMNA (0.38) LMNASMN1; SMN2MEN1KMT2APOLB
SCHEMBL30954070 0.77 S1PR1 (0.34) DRD2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed