Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 3/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876102 | 0.82 | AURKA (0.36) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL26145674 | 0.81 | AURKA (0.36) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL24786826 | 0.78 | CFB (0.34) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL30023280 | 0.78 | CFB (0.34) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL26077499 | 0.75 | P2RX7 (0.32) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL15704619 | 0.73 | P2RX7 (0.41) | ASH1LTNFRIPK1P2RX7KDM4E | |
| SCHEMBL12522435 | 0.72 | TNF (0.39) | ASH1LTNFRIPK1P2RX7KDM4E | |
| SCHEMBL2123165 | 0.70 | P2RX7 (0.41) | AURKATPX2RPS6KA3DYRK1ADAPK3 | |
| SCHEMBL26145363 | 0.70 | AURKA (0.34) | AURKATPX2P2RX7GPR84 | |
| SCHEMBL15102902 | 0.70 | CCR8 (0.40) | AURKATPX2DYRK1AP2RX7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897376-A | Heterocyclic compounds and process for preparing same | 光明智慧生物科学公司 | 2024-04-16 | — | — | CN | disclosed |