Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311286 | 1.00 | PDE4A (0.40) | PDE4ACDK5CDK5R1PARP1 | |
| SCHEMBL21292087 | 0.77 | PDE4A (0.40) | PDE4A | |
| SCHEMBL27312317 | 0.77 | P2RX7 (0.35) | PARP1 | |
| SCHEMBL18330334 | 0.77 | PDE4A (0.68) | PDE4A | |
| SCHEMBL30954516 | 0.76 | CDK5 (0.41) | PDE4ACDK5CDK5R1 | |
| SCHEMBL27312680 | 0.76 | CDK5 (0.41) | PDE4ACDK5CDK5R1 | |
| SCHEMBL21292085 | 0.75 | PDE4A (0.63) | PDE4A | |
| SCHEMBL27312167 | 0.74 | PDE4A (0.58) | PDE4A | |
| SCHEMBL18322296 | 0.73 | PDE4A (0.69) | PDE4A | |
| SCHEMBL27312235 | 0.71 | PDE4A (0.71) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |