Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 14/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312680 | 1.00 | CDK5 (0.41) | CDK5CDK5R1PDE4AMAPKAPK2RPS6KA3 | |
| SCHEMBL30954490 | 0.76 | PDE4A (0.40) | CDK5CDK5R1PDE4A | |
| SCHEMBL27311286 | 0.76 | PDE4A (0.40) | CDK5CDK5R1PDE4A | |
| SCHEMBL27312683 | 0.74 | PDE4A (0.61) | PDE4A | |
| SCHEMBL27312557 | 0.72 | PDE4A (0.43) | CDK5CDK5R1PDE4ATSHRGFER | |
| SCHEMBL30954513 | 0.71 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3ALOX5 | |
| SCHEMBL30954512 | 0.71 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3ALOX5 | |
| SCHEMBL27311469 | 0.71 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3ALOX5 | |
| SCHEMBL27312679 | 0.71 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3ALOX5 | |
| SCHEMBL18330235 | 0.69 | PDE4A (0.50) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |