Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 8/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311284 | 1.00 | PARP1 (0.44) | PARP1RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL13629395 | 0.78 | RPS6KA5 (0.34) | CDC7 | |
| SCHEMBL27312316 | 0.77 | RPS6KA3 (0.38) | PARP1RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL1393632 | 0.76 | RPS6KA3 (0.53) | PARP1RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL30172384 | 0.76 | RPS6KA3 (0.53) | PARP1RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL22578499 | 0.76 | PARP1 (0.53) | PARP1RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL30954512 | 0.74 | MAPKAPK2 (0.47) | RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL30954513 | 0.74 | MAPKAPK2 (0.47) | RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL27311469 | 0.74 | MAPKAPK2 (0.47) | RPS6KA3MAPKAPK2HRH3RPS6KA2 | |
| SCHEMBL27312679 | 0.74 | MAPKAPK2 (0.47) | RPS6KA3MAPKAPK2HRH3RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |