Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954513 | 1.00 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3CDK1RPS6KA2 | |
| SCHEMBL27311469 | 1.00 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3CDK1RPS6KA2 | |
| SCHEMBL27312679 | 1.00 | MAPKAPK2 (0.47) | MAPKAPK2RPS6KA3HRH3CDK1RPS6KA2 | |
| SCHEMBL27311981 | 0.77 | MAPKAPK2 (0.40) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL27311626 | 0.77 | MAPKAPK2 (0.40) | MAPKAPK2RPS6KA3HRH3ALOX5 | |
| SCHEMBL4751694 | 0.77 | HRH3 (0.52) | MAPKAPK2RPS6KA3HRH3RPS6KA2ALOX5 | |
| SCHEMBL27311284 | 0.74 | PARP1 (0.44) | MAPKAPK2RPS6KA3HRH3RPS6KA2 | |
| SCHEMBL30954503 | 0.74 | PARP1 (0.44) | MAPKAPK2RPS6KA3HRH3RPS6KA2 | |
| SCHEMBL30954504 | 0.72 | SMYD2 (0.35) | MAPKAPK2RPS6KA3 | |
| SCHEMBL30954498 | 0.72 | SMYD2 (0.35) | MAPKAPK2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |