Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954637 | 0.81 | PRMT5 (0.45) | AAK1TDP1PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL30954635 | 0.74 | PRMT5 (0.48) | AAK1PRMT5WDR77GLS | |
| SCHEMBL24619251 | 0.70 | PRMT5 (0.48) | AAK1PRMT5WDR77SMN1; SMN2MAPK1 | |
| SCHEMBL29925213 | 0.70 | PRMT5 (0.48) | AAK1PRMT5WDR77GLS | |
| SCHEMBL20095411 | 0.70 | PRMT5 (0.48) | AAK1PRMT5WDR77GLS | |
| SCHEMBL29924642 | 0.70 | PRMT5 (0.48) | AAK1PRMT5WDR77SMN1; SMN2MAPK1 | |
| SCHEMBL7403833 | 0.69 | ADRB2 (0.44) | ALDH1A1TDP1CA1CA2MAPT | |
| SCHEMBL30421137 | 0.69 | CA12 (0.48) | AAK1BCHECNR2PRMT5WDR77 | |
| SCHEMBL8650989 | 0.69 | PTPN1 (0.40) | ALDH1A1TDP1SMN1; SMN2CA1CA2 | |
| SCHEMBL31591670 | 0.68 | BCHE (0.48) | AAK1ALDH1A1TDP1BCHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610262-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | Artivila Biopharma (CN) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088189-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2024-05-02 | — | — | WO | disclosed |