SCHEMBL30954741

SCHEMBL30954741

Oc1ccc(N=Nc2ccc3scnc3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
POLB P06746 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTK6 Q13882 2/20 0.44
EGFR P00533 1/20 0.43
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
KMT2A Q03164 2/20 0.42
HSP90AA1 P07900 1/20 0.42
RAB9A P51151 1/20 0.42
HSD17B10 Q99714 1/20 0.40
GLB1 P16278 1/20 0.40
CTRB1 P17538 1/20 0.40
CTRC Q99895 1/20 0.40
MAP3K11 Q16584 1/20 0.38
NAMPT P43490 1/20 0.37
HSD11B1 P28845 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29265410 1.00 ALDH1A1 (0.45) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL927314 0.80 ALDH1A1 (0.50) ALDH1A1HPGDSMN1; SMN2L3MBTL1PTK6
SCHEMBL29720591 0.80 ALDH1A1 (0.50) ALDH1A1HPGDSMN1; SMN2L3MBTL1PTK6
Hydrochloric Acid SCHEMBL31731478 0.78 ALDH1A1 (0.48) ALDH1A1HPGDSMN1; SMN2L3MBTL1PTK6
SCHEMBL1852870 0.77 FFAR1 (0.48) ALDH1A1EGFRMEN1KMT2AHSD17B10
SCHEMBL13394608 0.77 APP (0.40) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL29287698 0.75 ALDH1A1 (0.41) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL31314979 0.74 ALDH1A1 (0.58) ALDH1A1POLBHPGDSMN1; SMN2L3MBTL1
SCHEMBL28215553 0.74 RIPK2 (0.50) ALDH1A1POLBL3MBTL1EGFRMAPT
SCHEMBL29265295 0.72 NPC1 (0.47) ALDH1A1HPGDL3MBTL1EGFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290352-A Azo compound, preparation method and application thereof, and medicinal composition 四川大学 2024-07-05 CN disclosed