Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NNMT | P40261 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931914 | 0.91 | NNMT (0.50) | MAPTNNMTGAAATMMEN1 | |
| SCHEMBL3244089 | 0.79 | MAPK1 (0.47) | MAPTNNMTGAANQO2ALDH1A1 | |
| SCHEMBL5956248 | 0.78 | NNMT (0.46) | MAPTNNMTGAAMEN1USP2 | |
| SCHEMBL474122 | 0.77 | KDM4E (0.44) | MAPTNNMTGAANQO2MEN1 | |
| SCHEMBL29551416 | 0.77 | KDM4E (0.44) | MAPTNNMTGAANQO2MEN1 | |
| SCHEMBL31280472 | 0.76 | NNMT (0.41) | MAPTNNMTGAANQO2ATR | |
| SCHEMBL24553897 | 0.76 | NNMT (0.51) | MAPTNNMTGAAMEN1USP2 | |
| SCHEMBL8495483 | 0.76 | GAA (0.42) | MAPTNNMTGAANQO2MEN1 | |
| SCHEMBL2217864 | 0.76 | GAA (0.42) | MAPTNNMTGAAATMNQO2 | |
| SCHEMBL4347479 | 0.76 | NNMT (0.51) | MAPTNNMTGAAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635949-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024125395-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | 江苏恩华药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |