Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121006 | 0.80 | HTT (0.44) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL11565926 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AKDM1AMEN1 | |
| SCHEMBL26926130 | 0.78 | CTSB (0.43) | SMN1; SMN2NPC1RAB9AKDM1AMEN1 | |
| SCHEMBL16212149 | 0.77 | KDM1A (0.54) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL31024591 | 0.77 | KDM1A (0.54) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL15504877 | 0.76 | MEN1 (0.57) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL30732662 | 0.76 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30954940 | 0.76 | MEN1 (0.43) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL6285065 | 0.75 | MEN1 (0.53) | SMN1; SMN2NPC1RAB9ARORCKDM1A | |
| SCHEMBL631190 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ARORCKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626546-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024116086-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-06 | — | — | WO | disclosed |