Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 14/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926487 | 1.00 | VCAM1 (0.47) | VCAM1LPLLIPGALDH1A1LMNA | |
| SCHEMBL28453522 | 0.88 | TSHR (0.49) | LPLLIPGALDH1A1LMNAMAPT | |
| SCHEMBL29398685 | 0.83 | MAPT (0.45) | LPLLIPGALDH1A1MAPTHPGD | |
| SCHEMBL4550135 | 0.83 | ALDH1A1 (0.47) | LPLLIPGALDH1A1LMNAMAPT | |
| SCHEMBL3678053 | 0.83 | MAPT (0.45) | LPLLIPGALDH1A1MAPTHPGD | |
| SCHEMBL190588 | 0.83 | TDP1 (0.54) | LPLLIPGALDH1A1LMNAMAPT | |
| SCHEMBL2489484 | 0.82 | ALDH1A1 (0.56) | VCAM1LPLLIPGALDH1A1LMNA | |
| SCHEMBL14158127 | 0.82 | ALDH1A1 (0.56) | LPLLIPGALDH1A1LMNAMAPT | |
| SCHEMBL4771663 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL1237710 | 0.79 | ALDH1A1 (0.41) | LPLLIPGALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638441-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024133499-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) | 2024-06-27 | — | — | WO | disclosed |