Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29229341 | 1.00 | CYP2C19 (0.58) | CYP2C19PKMHTR6MEN1KMT2A | |
| SCHEMBL17844813 | 0.86 | L3MBTL1 (0.59) | CYP2C19PKMHTR6KMT2AALDH1A1 | |
| SCHEMBL30684920 | 0.82 | CYP2C19 (0.58) | CYP2C19PKMHTR6MEN1KMT2A | |
| SCHEMBL30685172 | 0.81 | FGFR4 (0.57) | HTR6MEN1KMT2AFGFR4L3MBTL1 | |
| SCHEMBL29277237 | 0.81 | FGFR4 (0.57) | HTR6MEN1KMT2AFGFR4L3MBTL1 | |
| SCHEMBL2011040 | 0.79 | CYP2C19 (0.61) | CYP2C19PKMHTR6MEN1KMT2A | |
| SCHEMBL17714319 | 0.78 | MET (0.57) | CYP2C19PKMHTR6MEN1KMT2A | |
| SCHEMBL10142546 | 0.78 | CYP2C19 (0.61) | CYP2C19PKMHTR6MEN1KMT2A | |
| SCHEMBL16580886 | 0.78 | FGFR4 (0.41) | CYP2C19PKMALDH1A1TSHRHTT | |
| SCHEMBL27891832 | 0.78 | CYP2C19 (0.64) | CYP2C19PKMHTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070915-A1 | SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS | INCYTE CORP (US) | 2026-03-12 | — | — | US | disclosed |
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |
| CN-118184658-A | USP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070915-A1 | SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS | CDK4, CDK2, CCNC | CYP2C19 1448/4885PKM 1757/4885HTR6 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.