Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956099 | 0.85 | PSMB5 (0.46) | MAOBPSMB5MAPT | |
| SCHEMBL30956072 | 0.80 | ALDH1A1 (0.41) | MAOBPSMB5ALDH1A1MAOACA2 | |
| SCHEMBL11729224 | 0.78 | MAOB (0.79) | MAOBPSMB5MAPTCA2 | |
| SCHEMBL30956089 | 0.78 | CYP11B1 (0.51) | MAOBPSMB5MAPTCA2NPSR1 | |
| SCHEMBL30956084 | 0.77 | PSMB5 (0.46) | MAOBPSMB5ALDH1A1MAPTCA2 | |
| SCHEMBL30956090 | 0.75 | MAOB (0.59) | MAOBPSMB5ALDH1A1MAPTMAOA | |
| SCHEMBL21449482 | 0.72 | HDAC3 (0.44) | MAOBAPPALDH1A1MAPTHTT | |
| SCHEMBL30956063 | 0.71 | MAOB (0.49) | MAOBALDH1A1MAPTHTTCA2 | |
| SCHEMBL2433694 | 0.70 | APP (0.69) | MAOBAPPALDH1A1MAPTHTT | |
| SCHEMBL30956071 | 0.70 | CA2 (0.41) | MAOBPSMB5MAOACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005692-A | Preparation of benzofuran derivative by initiating free radical reaction by superelectron donor with heteroatom as center and application | 贵州大学 | 2024-05-10 | — | — | CN | disclosed |