Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | PTPRC | P08575 | 2/20 | 0.83 |
| ▸ | TDP2 | O95551 | 3/20 | 0.73 |
| ▸ | NSD2 | O96028 | 3/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.73 |
| ▸ | ABL1 | P00519 | 1/20 | 0.73 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.73 |
| ▸ | CES1 | P23141 | 1/20 | 0.73 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | S100A4 | P26447 | 6/20 | 0.65 |
| ▸ | CDC25B | P30305 | 3/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.64 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phanquone SCHEMBL462025 | 1.00 | MEN1 (1.00) | MEN1THRBBLMKMT2ATDP1 | |
| Phanquone SCHEMBL7633567 | 1.00 | MEN1 (1.00) | MEN1THRBBLMKMT2ATDP1 | |
| Phanquone SCHEMBL30659794 | 1.00 | MEN1 (1.00) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL730769 | 0.95 | MEN1 (0.90) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL29503833 | 0.95 | MEN1 (0.90) | MEN1THRBBLMKMT2ATDP1 | |
| Bromide SCHEMBL28112336 | 0.92 | MEN1 (0.86) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL4047045 | 0.91 | PTPRC (1.00) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL5915065 | 0.90 | TDP2 (0.81) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL460626 | 0.88 | TDP2 (0.78) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL1899280 | 0.88 | PTPRC (0.88) | MEN1THRBBLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255765-A | Spiro nitrogen-containing compound and application thereof | 安徽晶凯电子材料有限公司 | 2024-06-28 | — | — | CN | disclosed |