SCHEMBL4047045

SCHEMBL4047045

O=C1C(=O)c2ncccc2-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 1.00
MEN1 O00255 2/20 0.83
THRB P10828 2/20 0.83
BLM P54132 2/20 0.83
KMT2A Q03164 2/20 0.83
TDP1 Q9NUW8 1/20 0.83
CTSL P07711 1/20 0.73
CTSS P25774 1/20 0.73
PTPN13 Q12923 1/20 0.73
TDP2 O95551 4/20 0.68
NSD2 O96028 3/20 0.68
PAX8 Q06710 3/20 0.68
PLCG1 P19174 2/20 0.68
CES1 P23141 2/20 0.68
ABL1 P00519 1/20 0.68
RIN1 Q13671 1/20 0.68
GAA P10253 1/20 0.61
ALDH1A1 P00352 1/20 0.57
S100A4 P26447 6/20 0.57
CDC25B P30305 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899280 0.93 PTPRC (0.88) PTPRCMEN1THRBBLMKMT2A
SCHEMBL29566445 0.93 PTPRC (0.88) PTPRCMEN1THRBBLMKMT2A
Bromide SCHEMBL28836578 0.91 PTPRC (0.84) PTPRCMEN1THRBBLMKMT2A
Phanquone SCHEMBL462025 0.91 MEN1 (1.00) PTPRCMEN1THRBBLMKMT2A
Phanquone SCHEMBL30956643 0.91 MEN1 (1.00) PTPRCMEN1THRBBLMKMT2A
Phanquone SCHEMBL7633567 0.91 MEN1 (1.00) PTPRCMEN1THRBBLMKMT2A
Phanquone SCHEMBL30659794 0.91 MEN1 (1.00) PTPRCMEN1THRBBLMKMT2A
SCHEMBL29503833 0.86 MEN1 (0.90) PTPRCMEN1THRBBLMKMT2A
SCHEMBL730769 0.86 MEN1 (0.90) PTPRCMEN1THRBBLMKMT2A
SCHEMBL1103717 0.84 GAA (0.78) PTPRCMEN1THRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377329-A Perovskite solar cell containing azaphenanthrenequinone additive 中国科学院合肥物质科学研究院 2024-01-09 CN claimed
EP-1242086-B1 CD45 INHIBITORS ASTRAZENECA AB (SE) 2005-10-05 EP claimed
US-20030130298-A1 Cd45 inhibitors ASTRAZENECA AB (SE) 2003-07-10 US claimed
EP-1242086-A2 CD45 INHIBITORS AstraZeneca AB (SE) 2002-09-25 EP claimed
WO-2001045680-A2 CD45 INHIBITORS ASTRAZENECA AB (SE) 2001-06-28 WO claimed
CN-121405886-B Phenanthrenequinone-based covalent organic framework material, nano preparation containing same, preparation method of phenanthrenequinone-based covalent organic framework material and biomedical application of phenanthrenequinone-based covalent organic framework material 四川大学 2026-03-31 CN disclosed
CN-121405886-A Phenanthrenequinone-based covalent organic framework material, nano preparation containing same, preparation method of phenanthrenequinone-based covalent organic framework material and biomedical application of phenanthrenequinone-based covalent organic framework material 四川大学 2026-01-27 CN disclosed
CN-117843931-A Azaquinone-based polymer material, and preparation method and application thereof 井冈山大学 2024-04-09 CN disclosed
CN-117377329-A Perovskite solar cell containing azaphenanthrenequinone additive 中国科学院合肥物质科学研究院 2024-01-09 CN disclosed
CN-117377329-A Perovskite solar cell containing azaphenanthrenequinone additive 中国科学院合肥物质科学研究院 2024-01-09 CN disclosed
CN-117377329-A Perovskite solar cell containing azaphenanthrenequinone additive 中国科学院合肥物质科学研究院 2024-01-09 CN disclosed
US-20090209571-A1 Phenanthrene derivatives as MPGES-1 inhibitors CELLUMEN INC. 2009-08-20 US disclosed
EP-2024371-A1 PHENANTHRENE DERIVATIVES AS MPGES-1 INHIBITORS Merck Frosst Canada Ltd. (CA) 2009-02-18 EP disclosed
WO-2007134434-A1 PHENANTHRENE DERIVATIVES AS MPGES-1 INHIBITORS MERCK FROSST CANADA LTD. (CA) 2007-11-29 WO disclosed
EP-1242086-B1 CD45 INHIBITORS ASTRAZENECA AB (SE) 2005-10-05 EP disclosed
US-20030130298-A1 Cd45 inhibitors ASTRAZENECA AB (SE) 2003-07-10 US disclosed
EP-1242086-A2 CD45 INHIBITORS AstraZeneca AB (SE) 2002-09-25 EP disclosed
WO-2001045680-A2 CD45 INHIBITORS ASTRAZENECA AB (SE) 2001-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209571-A1 Phenanthrene derivatives as MPGES-1 inhibitors PTGES, PTGS1, PTGES2 PTPRC 2968/4885MEN1 3762/4885THRB 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.