Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572368 | 0.94 | ALDH1A1 (0.62) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL5449585 | 0.84 | ALDH1A1 (0.67) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL5123738 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL16266238 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL15528340 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL30646454 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL24575916 | 0.81 | EPHX2 (0.83) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL14694017 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL18415483 | 0.81 | POLB (0.77) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL1490952 | 0.81 | HPGD (0.76) | ALDH1A1HPGDPOLBTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009652-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIV ROCHESTER (US) | 2016-01-14 | — | — | US | claimed |
| US-20100233106-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIVERSITY OF ROCHESTER (US) | 2010-09-16 | — | — | US | claimed |
| WO-2008121850-A2 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIVERSITY OF ROCHESTER (US) | 2008-10-09 | — | — | WO | claimed |
| EP-0795596-B1 | Fuel compositions | SHELL INT RESEARCH (NL) | 2000-10-11 | — | — | EP | claimed |
| EP-0795596-A1 | Fuel compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-09-17 | — | — | EP | claimed |
| JP-9328691-A | — | — | None | — | — | JP | disclosed |
| CN-112898173-B | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-112898173-A | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2021-06-04 | — | — | CN | disclosed |
| US-20160009652-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIV ROCHESTER (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160009652-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIV ROCHESTER (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160009652-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIV ROCHESTER (US) | 2016-01-14 | — | — | US | disclosed |
| US-9162984-B2 | Small-molecule modulators of melanin expression | UNIVERSITY OF ROCHESTER (US) | 2015-10-20 | — | — | US | disclosed |
| US-20100233106-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIVERSITY OF ROCHESTER (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100233106-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIVERSITY OF ROCHESTER (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2008121850-A2 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | UNIVERSITY OF ROCHESTER (US) | 2008-10-09 | — | — | WO | disclosed |
| EP-0795596-B1 | Fuel compositions | SHELL INT RESEARCH (NL) | 2000-10-11 | — | — | EP | disclosed |
| CN-1225091-A | Substituted 1,3-benzodioxoles | AMERICAN HOME PROD (US) | 1999-08-04 | — | — | CN | disclosed |
| US-5925152-A | MIXTURE CONTAINING A FUEL ADDITIVE FURAN DERIVATIVE HAVING HETEROCYCLIC AND/OR ARYL CARBOCYCLIC GROUPS; ANTIDEPOSIT AGENTS, ANTIKNOCK COMPOUNDS | SHELL OIL COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| JP-H09328691-A | FUEL COMPOSITION | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1997-12-22 | — | — | JP | disclosed |
| EP-0795596-A1 | Fuel compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009652-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | TYR, MITF, MC1R | ALDH1A1 737/4885HPGD 339/4885POLB 4029/4885 |
| US-20100233106-A1 | SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION | TYR, MITF, MC1R | ALDH1A1 737/4885HPGD 339/4885POLB 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.