Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1440123 | 1.00 | SIRT3 (0.61) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL31291300 | 0.85 | KDM4E (0.66) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL9107394 | 0.85 | KDM4E (0.66) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL29416299 | 0.84 | KDM4E (0.70) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL68952 | 0.84 | KDM4E (0.70) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL3964969 | 0.83 | TDP1 (0.65) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL4591568 | 0.83 | TDP1 (0.65) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL5802324 | 0.83 | TDP1 (0.59) | SIRT3TDP1KDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL18204823 | 0.83 | KDM4E (0.64) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL6641437 | 0.82 | ALDH1A1 (0.50) | SIRT3TDP1KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612154-A1 | REGULATORS OF PORPHYRIN AND INTERMEDIATES | Madera Therapeutics, LLC (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2025137640-A1 | AZASPIRO WRN INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024097436-A1 | REGULATORS OF PORPHYRIN AND INTERMEDIATES | Madera Therapeutics, LLC (US) | 2024-05-10 | — | — | WO | disclosed |