Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16118580 | 0.85 | ALDH1A1 (0.50) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL1440123 | 0.83 | SIRT3 (0.61) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL30957166 | 0.83 | SIRT3 (0.61) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL5802324 | 0.81 | TDP1 (0.59) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL3964969 | 0.81 | TDP1 (0.65) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL29570949 | 0.80 | SIRT3 (0.58) | TDP1SIRT3ALDH1A1NPC1RAB9A | |
| SCHEMBL907851 | 0.80 | SIRT3 (0.58) | TDP1SIRT3ALDH1A1NPC1RAB9A | |
| Ethane SCHEMBL28930003 | 0.79 | SIRT3 (0.56) | TDP1SIRT3ALDH1A1NPC1RAB9A | |
| SCHEMBL16836475 | 0.79 | ALDH1A1 (0.47) | TDP1SIRT3ALDH1A1KDM4EGLA | |
| SCHEMBL28101840 | 0.79 | TDP1 (0.56) | TDP1SIRT3ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354579-B | High-yield synthesis method of methyl 4-aminonicotinate | 安徽大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |