SCHEMBL30957281

C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O

nearest known ligand 0.47

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.47

▸	MAPK9	P45984	1/20	0.47

▸	MAPK10	P53779	1/20	0.47

▸	EPHA2	P29317	2/20	0.42

▸	OPRM1	P35372	7/20	0.41

▸	OPRK1	P41145	7/20	0.41

▸	RAMP3	O60896	7/20	0.41

▸	CALCR	P30988	7/20	0.41

▸	IL23R	Q5VWK5	1/20	0.40

▸	CXCR4	P61073	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30868648	0.93	IL23R (0.43)	MAPK8MAPK9MAPK10RAMP3CALCR
SCHEMBL30868607	0.93	RAMP3 (0.46)	MAPK8MAPK9MAPK10EPHA2OPRM1
SCHEMBL30957282	0.93	EPHA2 (0.49)	MAPK8MAPK9MAPK10EPHA2OPRM1
SCHEMBL31265332	0.86	ACE (0.43)	EPHA2OPRM1OPRK1
SCHEMBL29801838	0.86	OPRM1 (0.52)	EPHA2OPRM1OPRK1CXCR4
SCHEMBL30868635	0.85	KEAP1 (0.45)	EPHA2RAMP3CALCRCXCR4
SCHEMBL30868640	0.85	NMUR2 (0.44)	MAPK8MAPK9MAPK10RAMP3CALCR
SCHEMBL29905998	0.85	KEAP1 (0.45)	EPHA2RAMP3CALCRCXCR4
SCHEMBL14028315	0.85	RAMP3 (0.46)	RAMP3CALCR
Risuteganib SCHEMBL13827707	0.85	RAMP3 (0.42)	MAPK8MAPK9MAPK10RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4389216-A2	PEPTIDE COMPOSITIONS AND THERAPEUTIC USES	Allegro Pharmaceuticals, LLC (US)	2024-06-26	—	—	EP	disclosed