SCHEMBL30957286

SCHEMBL30957286

O=[N+]([O-])c1cc2c(cc1F)C(O)CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HIF1A Q16665 1/20 0.38
EPAS1 Q99814 1/20 0.36
VCAM1 P19320 1/20 0.36
ESPL1 Q14674 1/20 0.36
PIN1 Q13526 3/20 0.35
MAPT P10636 4/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PGR P06401 1/20 0.34
STS P08842 1/20 0.34
CYP19A1 P11511 1/20 0.34
TBXA2R P21731 1/20 0.34
PPIA P62937 1/20 0.34
PPID Q08752 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30951231 0.94 ESPL1 (0.39) ATMTDP1ALDH1A1HIF1AEPAS1
SCHEMBL29284988 0.94 ESPL1 (0.39) ATMTDP1ALDH1A1HIF1AEPAS1
SCHEMBL30951195 0.78 ALDH1A1 (0.41) ALDH1A1EPAS1VCAM1MAPTLMNA
SCHEMBL29284908 0.78 ALDH1A1 (0.41) ALDH1A1EPAS1VCAM1MAPTLMNA
SCHEMBL5199935 0.77 CYP19A1 (0.35) PGRCYP19A1
SCHEMBL19559419 0.76 MEN1 (0.38) ALDH1A1MAPTLMNAHTTMEN1
SCHEMBL31533411 0.75 MAP3K14 (0.43) ATMTDP1ALDH1A1HIF1AESPL1
SCHEMBL31533478 0.74 ALDH1A1 (0.35) ATMTDP1ALDH1A1ESPL1MAPT
SCHEMBL18094359 0.71 KDM1A (0.41) PGRCYP19A1
SCHEMBL4647775 0.71 ATM (0.44) ATMTDP1ALDH1A1HIF1AVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598933-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF Allorion Therapeutics Inc (US) 2025-08-13 EP disclosed
CN-119968377-A Phosphoramidate compounds and uses thereof 安锐生物医药公司 2025-05-09 CN disclosed
WO-2024078392-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2024-04-18 WO disclosed