SCHEMBL30957360

SCHEMBL30957360

Oc1ccc(-c2ncc(F)cn2)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.48
ESR2 Q92731 7/20 0.48
FGFR1 P11362 1/20 0.43
FGFR2 P21802 1/20 0.43
USP7 Q93009 2/20 0.41
AR P10275 2/20 0.40
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27631730 1.00 ESR1 (0.48) ESR1ESR2FGFR1FGFR2USP7
SCHEMBL12987550 0.78 ESR1 (0.46) ESR1ESR2FGFR1FGFR2USP7
SCHEMBL12892354 0.77 HDAC1 (0.39) HDAC1HDAC8HDAC6HDAC5
SCHEMBL29557461 0.76 ESR1 (0.74) ESR1ESR2FGFR1FGFR2AR
SCHEMBL2862424 0.76 ESR1 (0.74) ESR1ESR2FGFR1FGFR2AR
SCHEMBL8555801 0.74 RAB9A (0.49) ESR1USP7
SCHEMBL14818817 0.74 ESR1 (0.49) ESR1ESR2FGFR1FGFR2USP7
SCHEMBL30957336 0.74 MAOB (0.42) ESR1ESR2
SCHEMBL9171667 0.73 NR5A1 (0.51) USP7
SCHEMBL8520094 0.73 NR5A1 (0.51) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598933-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF Allorion Therapeutics Inc (US) 2025-08-13 EP disclosed
CN-119968377-A Phosphoramidate compounds and uses thereof 安锐生物医药公司 2025-05-09 CN disclosed
WO-2024078392-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2024-04-18 WO disclosed