SCHEMBL30957368

SCHEMBL30957368

Cc1ccccc1N(CCCCCCN(C(=O)O)c1ccccc1C)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.61
ALDH1A1 P00352 1/20 0.61
TRPM8 Q7Z2W7 1/20 0.55
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CYP3A4 P08684 2/20 0.47
LMNA P02545 2/20 0.47
NPC1 O15118 1/20 0.43
JAK2 O60674 1/20 0.43
RAB9A P51151 1/20 0.43
PAX8 Q06710 1/20 0.43
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
POLB P06746 1/20 0.40
BCHE P06276 2/20 0.40
ACHE P22303 2/20 0.40
TEAD1 P28347 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30957369 1.00 TP53 (0.61) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL30957352 0.82 TP53 (0.47) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL7653267 0.81 CYP3A4 (0.63) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL11709815 0.80 TRPM8 (0.57) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL30957296 0.77 TP53 (0.46) TP53ALDH1A1NPC1JAK2RAB9A
SCHEMBL11446155 0.76 ALDH1A1 (0.62) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL11498178 0.76 TRPM8 (0.53) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL11652965 0.76 TRPM8 (0.56) TP53ALDH1A1TRPM8KMT2AMEN1
SCHEMBL30957339 0.76 NPC1 (0.51) TP53ALDH1A1NPC1JAK2RAB9A
SCHEMBL5514063 0.76 NPC1 (0.51) TP53ALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed