Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900572 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1MAPK1MAPTTSHR | |
| SCHEMBL30957623 | 0.86 | TERT (0.47) | SMN1; SMN2NPC1MAPK1TSHRHTT | |
| SCHEMBL24900601 | 0.86 | TERT (0.47) | SMN1; SMN2NPC1MAPK1TSHRHTT | |
| SCHEMBL8966015 | 0.84 | NPC1 (0.54) | NPC1MAPK1MAPTALDH1A1CA1 | |
| SCHEMBL6819793 | 0.82 | MAPT (0.51) | SMN1; SMN2MAPTALDH1A1CA1CA2 | |
| SCHEMBL4019536 | 0.82 | MAPT (0.47) | SMN1; SMN2MAPTALDH1A1RAD52POLB | |
| SCHEMBL24900467 | 0.78 | NCF1 (0.43) | NPC1MAPTALDH1A1CA1CA2 | |
| SCHEMBL3141594 | 0.78 | MAPT (0.40) | MAPTHTTALDH1A1RAD52CA1 | |
| SCHEMBL24900657 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPK1MAPTALDH1A1POLB | |
| SCHEMBL30957579 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPK1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |