Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | DPYD | Q12882 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192399 | 1.00 | LMNA (0.62) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL192400 | 1.00 | LMNA (0.62) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL24385991 | 1.00 | LMNA (0.62) | LMNAMEN1KMT2ATHRBBLM | |
| (Z)-1,2-Diphenylethene SCHEMBL7653143 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| SCHEMBL44502 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| SCHEMBL6360540 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| SCHEMBL44503 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL7653150 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| SCHEMBL9540538 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB | |
| SCHEMBL5411617 | 0.87 | NFE2L2 (0.68) | MEN1KMT2ANFE2L2TRPA1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903135-A | Method for preparing fullerene pyrrolidine tetrahydroisoquinoline based on participation of o-styryl benzaldehyde | 湖北大学 | 2024-04-19 | — | — | CN | claimed |
| CN-118561840-A | Synthesis method of dihydroimidazo [2,1-a ] isoquinoline derivatives | 海南医学院 | 2024-08-30 | — | — | CN | disclosed |
| CN-117903135-A | Method for preparing fullerene pyrrolidine tetrahydroisoquinoline based on participation of o-styryl benzaldehyde | 湖北大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117903135-A | Method for preparing fullerene pyrrolidine tetrahydroisoquinoline based on participation of o-styryl benzaldehyde | 湖北大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117903135-A | Method for preparing fullerene pyrrolidine tetrahydroisoquinoline based on participation of o-styryl benzaldehyde | 湖北大学 | 2024-04-19 | — | — | CN | disclosed |