Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30975988 | 0.86 | KHK (0.30) | — | |
| SCHEMBL24758326 | 0.82 | KMT2A (0.34) | ALDH1A1KDM4EHPGDMAPTTP53 | |
| SCHEMBL24906254 | 0.82 | KDM4E (0.33) | ALDH1A1KDM4EHPGDMAPTTP53 | |
| SCHEMBL24906208 | 0.79 | KDM4E (0.32) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL30141513 | 0.79 | KDM4E (0.32) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL30976103 | 0.79 | KDM4E (0.33) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL30141514 | 0.78 | KDM4E (0.31) | ALDH1A1KDM4EHPGD | |
| SCHEMBL30141538 | 0.77 | KDM4E (0.32) | ALDH1A1KDM4EHPGDMAPTTP53 | |
| SCHEMBL30975972 | 0.76 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDTP53KMT2A | |
| SCHEMBL27417561 | 0.75 | KDM4E (0.33) | ALDH1A1KDM4EHPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-4385979-A1 | MULTICYCLIC INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |