SCHEMBL30958855

SCHEMBL30958855

COc1cc(C=C(NC(C)=O)C(=O)O)ccc1OC(C)=O

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.72
MAPT P10636 1/20 0.65
JUN P05412 1/20 0.59
NFKB1 P19838 1/20 0.59
KMT2A Q03164 2/20 0.53
VCP P55072 1/20 0.51
RAB9A P51151 2/20 0.50
GAA P10253 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
MCL1 Q07820 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10747248 1.00 ALDH1A1 (0.72) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL2457107 1.00 ALDH1A1 (0.72) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL2457110 1.00 ALDH1A1 (0.72) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL11289654 0.95 ALDH1A1 (0.65) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL2457625 0.93 ALDH1A1 (0.62) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL2457630 0.93 ALDH1A1 (0.62) ALDH1A1MAPTJUNNFKB1KMT2A
SCHEMBL6449146 0.92 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ARAB9AGAA
SCHEMBL10466948 0.92 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ARAB9AGAA
SCHEMBL6449141 0.92 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ARAB9AGAA
SCHEMBL11938178 0.90 ALDH1A1 (0.72) ALDH1A1MAPTJUNNFKB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307428-B Chiral alpha unnatural amino acid and preparation method thereof by rare noble metal complex 北京元延医药科技股份有限公司 2025-01-10 CN disclosed
CN-118307428-A Chiral alpha unnatural amino acid and preparation method thereof by rare noble metal complex 北京元延医药科技股份有限公司 2024-07-09 CN disclosed