Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31671147 | 0.81 | CYP1A2 (0.40) | TSHRLMNAALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6651373 | 0.77 | TSHR (0.55) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL14472065 | 0.76 | ALOX15 (0.34) | HSD17B10 | |
| SCHEMBL27861576 | 0.75 | TSHR (0.39) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13191103 | 0.74 | ALDH1A1 (0.33) | TSHRLMNAALDH1A1HSD17B10MGAM | |
| SCHEMBL10535267 | 0.73 | — | — | |
| SCHEMBL11365507 | 0.73 | MGAM (0.38) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL19821796 | 0.72 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| Cyclopropane SCHEMBL27365076 | 0.72 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL26205587 | 0.72 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615849-A1 | CYCLIC BENZIMIDAZOLE DERIVATIVES AS CGAS INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099907-A1 | CYCLIC BENZIMIDAZOLE DERIVATIVES AS CGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |