Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26537645 | 0.84 | SETD7 (0.38) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL6745485 | 0.84 | SETD7 (0.38) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL24267329 | 0.84 | SETD7 (0.38) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL1197535 | 0.81 | SETD7 (0.40) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL432224 | 0.81 | SETD7 (0.40) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL1197830 | 0.81 | SETD7 (0.40) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| Ethylene SCHEMBL5865026 | 0.78 | SETD7 (0.39) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL29924611 | 0.78 | SETD7 (0.37) | SETD7MAP4K4USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL31708282 | 0.78 | ALDH1A1 (0.36) | USP2SMN1; SMN2HSD17B10NR1H2GPR119 | |
| SCHEMBL24815806 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2NR1H2GPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635958-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024125642-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-06-20 | — | — | WO | disclosed |