Sugi Predict

Sugi Predict / Compounds / SCHEMBL432224

SCHEMBL432224

SCHEMBL432224

CC1CC(=O)CCN1C(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SETD7 Q8WTS6 1/20 0.40
▸ USP2 O75604 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ MAP4K4 O95819 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ NR1H2 P55055 1/20 0.37
▸ DDB1 Q16531 1/20 0.36
▸ CRBN Q96SW2 1/20 0.36
▸ GPR119 Q8TDV5 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ CHRM2 P08172 1/20 0.36
▸ CHRM1 P11229 1/20 0.36
▸ CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1197830 1.00 SETD7 (0.40) SETD7USP2SMN1; SMN2MAP4K4HSD17B10
SCHEMBL1197535 1.00 SETD7 (0.40) SETD7USP2SMN1; SMN2MAP4K4HSD17B10
Ethylene SCHEMBL5865026 0.97 SETD7 (0.39) SETD7USP2SMN1; SMN2MAP4K4HSD17B10
SCHEMBL18198392 0.90 HSD17B10 (0.41) SETD7HSD17B10
SCHEMBL31080561 0.90 HSD17B10 (0.41) SETD7HSD17B10
SCHEMBL31080429 0.90 HSD17B10 (0.41) SETD7HSD17B10
SCHEMBL28315212 0.89 SETD7 (0.35) SETD7MAP4K4HSD17B10KDM4EMAPT
SCHEMBL18198355 0.87 SETD7 (0.39) SETD7HSD17B10KDM4EMAPTTHRB
SCHEMBL24267329 0.83 SETD7 (0.38) SETD7USP2SMN1; SMN2MAP4K4HSD17B10
SCHEMBL6745485 0.83 SETD7 (0.38) SETD7USP2SMN1; SMN2MAP4K4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 900 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103601669-B A kind of synthetic method of 1-tertbutyloxycarbonyl-2-methyl-4-piperidones 甘肃科瑞生物科技有限公司 2016-08-03 — — CN claimed
CN-103601669-A Synthesis method of 1-tertbutyloxycarbonyl-2-methyl-4-piperidone GANSU KERUI BIOLOG SCIENCE & TECHNOLOGY CO LTD 2014-02-26 — — CN claimed
US-12637467-B2 Inhibitor of BTK and mutants thereof NEWAVE PHARMACEUTICAL INC. (US) 2026-05-26 — — US disclosed
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 — — US disclosed
EP-4724443-A1 PYRAZOLO-PYRIMIDINONE COMPOUNDS FOR USE IN METHODS OF INHIBITING WEE1 A KINASE Acrivon Therapeutics, Inc. (US) 2026-04-15 — — EP disclosed
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2026-03-12 — — US disclosed
US-12551490-B2 Heterocyclic modulators of lipid synthesis SAGIMET BIOSCIENCES INC. (US) 2026-02-17 — — US disclosed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 — — US disclosed
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2026-01-01 — — US disclosed
US-20260000692-A1 Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors AURIGENE ONCOLOGY LIMITED (IN) 2026-01-01 — — US disclosed
EP-4661964-A1 COMPOUNDS AS CCR6 INHIBITORS F. Hoffmann-La Roche AG (CH) 2025-12-17 — — EP disclosed
CN-1407982-A Serotonergic benzofurans LILLY CO ELI (US) 2003-04-02 — — CN disclosed
EP-1244623-A1 A PROCESS FOR PREPARING 4-SUBSTITUTED PIPERIDINES ELI LILLY AND COMPANY (US) 2002-10-02 — — EP disclosed
EP-1242411-A1 INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND ANXIETY ELI LILLY AND COMPANY (US) 2002-09-25 — — EP disclosed
EP-1204659-A2 SEROTONERGIC BENZOFURANS ELI LILLY AND COMPANY (US) 2002-05-15 — — EP disclosed
EP-1204660-A1 SEROTONERGIC BENZOTHIOPHENES ELI LILLY AND COMPANY (US) 2002-05-15 — — EP disclosed
WO-2001046147-A1 A PROCESS FOR PREPARING 4-SUBSTITUTED PIPERIDINES ELI LILLY AND COMPANY (US) 2001-06-28 — — WO disclosed
WO-2001046181-A1 INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND ANXIETY ELI LILLY AND COMPANY (US) 2001-06-28 — — WO disclosed
WO-2001009126-A1 SEROTONERGIC BENZOTHIOPHENES ELI LILLY AND COMPANY (US) 2001-02-08 — — WO disclosed
WO-2001009122-A2 SEROTONERGIC BENZOFURANS ELI LILLY AND COMPANY (US) 2001-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D SETD7 3801/4885USP2 3457/4885SMN1; SMN2 1018/4885
US-20260000692-A1 Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors CDK1, CDK12, CDK11A SETD7 3914/4885USP2 2341/4885SMN1; SMN2 2065/4885
US-12637467-B2 Inhibitor of BTK and mutants thereof BTK, CNKSR1, SYK SETD7 1829/4885USP2 3490/4885SMN1; SMN2 4286/4885
US-12551490-B2 Heterocyclic modulators of lipid synthesis FASN, FADS1, FADS2 SETD7 962/4885USP2 1543/4885SMN1; SMN2 4623/4885
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 STAT6, NCOR1, NCOR2 SETD7 1544/4885USP2 3487/4885SMN1; SMN2 4101/4885
US-20260014147-A1 STAT6 DEGRADERS STAT6, NCOR1, CBR1 SETD7 2261/4885USP2 1210/4885SMN1; SMN2 2651/4885
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF CCR3, SCN1B, NR3C1 SETD7 3582/4885USP2 4159/4885SMN1; SMN2 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.