Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577553 | 1.00 | OPRK1 (0.60) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL30961066 | 0.91 | MAPT (0.57) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL23577599 | 0.91 | MAPT (0.57) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL2260830 | 0.87 | EGFR (0.62) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL3106139 | 0.86 | ABCG2 (0.72) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL24721300 | 0.85 | ABCG2 (0.75) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL29909639 | 0.85 | ABCG2 (0.75) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL23601761 | 0.83 | ABCG2 (0.62) | OPRK1KMT2AMAPTABCG2EGFR | |
| SCHEMBL30960996 | 0.82 | ABCG2 (0.52) | OPRK1KMT2AMAPTABCG2SMN1; SMN2 | |
| SCHEMBL23576951 | 0.82 | ABCG2 (0.52) | OPRK1KMT2AMAPTABCG2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | DGKG, DGKB, DGKK | OPRK1 1932/4885KMT2A 2566/4885MAPT 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.