Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961340 | 0.76 | MAP4K4 (0.41) | IRAK4GRM2 | |
| SCHEMBL30961334 | 0.72 | CCNC (0.37) | IRAK4GRM2PDE3BPDE3ANTRK1 | |
| SCHEMBL30961412 | 0.72 | FFAR1 (0.41) | IRAK4GRM2PIK3CDTTKPIK3CG | |
| SCHEMBL18797473 | 0.68 | FPR2 (0.43) | GRM2PDE3BPDE3ANTRK1CCNC | |
| SCHEMBL30961442 | 0.67 | FEN1 (0.43) | NTRK1TTK | |
| SCHEMBL30961387 | 0.67 | PIK3CD (0.40) | IRAK4GRM2PDE3BPDE3ANTRK1 | |
| SCHEMBL22715404 | 0.66 | — | — | |
| SCHEMBL30961311 | 0.65 | AKT1 (0.38) | — | |
| SCHEMBL30025242 | 0.64 | KDM4E (0.41) | GRM2PDE3BPDE3APIK3CDCCNC | |
| SCHEMBL23535770 | 0.64 | BCL2L1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125451-A1 | PIPERINDIN-ONES DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |