Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961387 | 0.81 | PIK3CD (0.40) | CCNCCDK8IRAK4AXLNTRK1 | |
| SCHEMBL17059253 | 0.78 | EGFR (0.35) | CCNCCDK8IRAK4ALOX5APTTK | |
| SCHEMBL30961364 | 0.76 | AXL (0.57) | IRAK4AXLGRM2TTK | |
| SCHEMBL19555915 | 0.74 | MKNK1 (0.37) | CCNCCDK8IRAK4NTRK1GRM2 | |
| SCHEMBL30961283 | 0.72 | IRAK4 (0.39) | CCNCCDK8IRAK4NTRK1GRM2 | |
| SCHEMBL30961453 | 0.72 | IRAK4 (0.41) | IRAK4AXLALOX5APTTKPIK3CD | |
| SCHEMBL30961397 | 0.70 | BTK (0.38) | AXLGRM2 | |
| SCHEMBL18797473 | 0.68 | FPR2 (0.43) | CCNCCDK8NTRK1GRM2PDE3B | |
| SCHEMBL30961365 | 0.67 | FEN1 (0.43) | AXLNTRK1 | |
| SCHEMBL25407249 | 0.67 | ALOX5AP (0.35) | CCNCCDK8GRM2ALOX5APPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125451-A1 | PIPERINDIN-ONES DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |