SCHEMBL309620

SCHEMBL309620

[CH2]C(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.62
ESR2 Q92731 12/20 0.62
CYP3A4 P08684 4/20 0.62
LMNA P02545 2/20 0.62
TYR P14679 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
AR P10275 1/20 0.62
TSHR P16473 1/20 0.62
SLC6A2 P23975 1/20 0.62
SLC6A4 P31645 1/20 0.62
HTR6 P50406 1/20 0.62
ESRRG P62508 1/20 0.62
SLC6A3 Q01959 1/20 0.62
ALDH1A1 P00352 3/20 0.52
SHBG P04278 1/20 0.50
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848806 0.83 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL766397 0.78 ESR1 (0.89) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL30041667 0.78 ESR1 (0.89) ESR1ESR2CYP3A4LMNATYR
SCHEMBL632450 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL14124344 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL14255700 0.77 ESR1 (0.54) ESR1ESR2CYP3A4LMNATYR
SCHEMBL7786692 0.77 ESR1 (0.52) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL9774987 0.77 ESR1 (1.00) ESR1ESR2CYP3A4LMNATYR
SCHEMBL3478499 0.77 ESR1 (0.52) ESR1ESR2CYP3A4LMNATYR
SCHEMBL22335854 0.77 ESR1 (0.80) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599532-B1 POLYMER COMPOSITIONS CONTAINING AN ULTRAVIOLET LIGHT ABSORBING COMPOUND EASTMAN CHEM CO (US) 2017-05-17 EP disclosed
US-8093316-B2 unexpected improvements in hydrolytic stability and weatherability of polycarbonate-polyester blends stabilized with phosphorus-containing catalyst quenchers and hindered amine light stabilizers EASTMAN CHEMICAL COMPANY (US) 2012-01-10 US disclosed
US-7491760-B2 Polymer compositions containing an ultraviolet light absorbing compound EASTMAN CHEMICAL COMPANY (US) 2009-02-17 US disclosed
US-7482397-B2 Polycarbonate compositions EASTMAN CHEMICAL COMPANY (US) 2009-01-27 US disclosed
US-7468409-B2 Polyester compositions EASTMAN CHEMICAL COMPANY (US) 2008-12-23 US disclosed
US-7425590-B2 Transparent two phase polyester-polycarbonate compositions EASTMAN CHEMICAL COMPANY (US) 2008-09-16 US disclosed
EP-1913088-A1 TRANSPARENT TWO PHASE POLYESTER-POLYCARBONATE COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2008-04-23 EP disclosed
EP-1902097-A2 POLYESTER-POLYCARBONATE COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2008-03-26 EP disclosed
EP-1585790-B1 POLYMER BLENDS EASTMAN CHEM CO (US) 2008-03-26 EP disclosed
US-7297735-B2 Polycarbonate compositions EASTMAN CHEMICAL COMPANY (US) 2007-11-20 US disclosed
US-5922816-A SILYL PHOSPHATE STABILIZER GENERAL ELECTRIC COMPANY (US) 1999-07-13 US disclosed
EP-0601784-B1 Stabilized polyester-polycarbonate compositions GEN ELECTRIC (US) 1999-03-17 EP disclosed
US-5502119-A ORGONOSILICATE GENERAL ELECTRIC COMPANY (US) 1996-03-26 US disclosed
EP-0615533-A1 FLAME RESISTANT THERMOPLASTIC BLENDS HAVING REDUCED DRIPPAGE GENERAL ELECTRIC COMPANY (US) 1994-09-21 EP disclosed
EP-0601784-A2 Stabilized polyester-polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1994-06-15 EP disclosed
WO-1994007956-A1 FLAME RESISTANT THERMOPLASTIC BLENDS HAVING REDUCED DRIPPAGE GENERAL ELECTRIC COMPANY (US) 1994-04-14 WO disclosed
EP-0017623-B1 HARDENABLE MIXTURES CONTAINING DIMETHYLAMINO DERIVATIVES CIBA-GEIGY AG (CH) 1984-03-07 EP disclosed
EP-0001616-B1 CURABLE EPOXY RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1981-07-22 EP disclosed
EP-0017623-A2 Hardenable mixtures containing dimethylamino derivatives CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
EP-0001616-A2 Curable epoxy resin compositions CIBA-GEIGY AG (CH) 1979-05-02 EP disclosed