SCHEMBL632450

SCHEMBL632450

CC(C)(N)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.62
ESR2 Q92731 10/20 0.62
CYP3A4 P08684 4/20 0.62
LMNA P02545 2/20 0.62
TYR P14679 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
AR P10275 1/20 0.62
TSHR P16473 1/20 0.62
SLC6A2 P23975 1/20 0.62
SLC6A4 P31645 1/20 0.62
HTR6 P50406 1/20 0.62
ESRRG P62508 1/20 0.62
SLC6A3 Q01959 1/20 0.62
ALDH1A1 P00352 3/20 0.52
SHBG P04278 1/20 0.50
PDE2A O00408 1/20 0.50
KIF11 P52732 1/20 0.48
BLM P54132 2/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1706121 0.85 PDE2A (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL14124344 0.83 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL7975886 0.81 ESR1 (0.59) ESR1ESR2CYP3A4LMNATYR
SCHEMBL7837799 0.79 ESR1 (0.56) ESR1ESR2CYP3A4LMNATYR
Hydrochloric Acid SCHEMBL6457601 0.79 ESR1 (0.56) ESR1ESR2CYP3A4LMNATYR
SCHEMBL29128909 0.79 ESR1 (0.56) ESR1ESR2CYP3A4LMNATYR
Bisphenol A SCHEMBL584084 0.78 ESR1 (0.89) ESR1ESR2CYP3A4LMNATYR
SCHEMBL5591445 0.78 PDE2A (0.50) ESR1ESR2CYP3A4LMNATYR
SCHEMBL678367 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR
SCHEMBL4449332 0.78 ESR1 (0.62) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438270-A Bonding dissimilar materials using radio frequency wave curing DDP特种电子材料美国有限责任公司 2023-07-14 CN claimed
CN-113929872-A Electron microscope embedding agent for embedding mouse brain tissue 西北农林科技大学 2022-01-14 CN claimed
CN-113454169-A Compositions comprising methylene malonate monomers and polymers, methods of making the same, and uses thereof in subterranean construction 巴斯夫欧洲公司 2021-09-28 CN claimed
EP-3713984-A1 ADHESIVE TAPES BASED ON EPOXY RESIN REACTIVE ADHESIVES TESA SE (DE) 2020-09-30 EP claimed
WO-2019101914-A1 ADHESIVE TAPES BASED ON EPOXY RESIN REACTIVE ADHESIVES TESA SE (DE) 2019-05-31 WO claimed
CN-109553871-A A kind of fresh-keeping thermal insulation material of refrigerator 江苏惠庆电器科技有限公司 2019-04-02 CN claimed
CN-109503795-A A kind of refrigerator heat insulation material 江苏惠庆电器科技有限公司 2019-03-22 CN claimed
CN-108084896-A Acrylate structural adhesive that a kind of flame retardant type power battery aluminum shell bonds and preparation method thereof 湖北回天新材料股份有限公司 2018-05-29 CN claimed
CN-107383674-A Flame-retardant PVC plastic 周小红 2017-11-24 CN claimed
CN-107325434-A PVC composites and preparation method thereof 周小红 2017-11-07 CN claimed
CN-101665562-A Preparation method of POSS-epoxy hybrid material with controllable phase structure UNIV XIAMEN 2010-03-10 CN claimed
CN-100363578-C Polyurethane rigid foam material for external thermal insulation system of external wall QINGDAO JINBEIJING ENGINEERING (CN) 2008-01-23 CN claimed
CN-1827978-A Polyurethane rigid foam material for external thermal insulation system of external wall QINGDAO JINBEIJING ENGINEERING (CN) 2006-09-06 CN claimed
CN-1515602-A Composite catalyst for improving size stability and its asphalt polyurethane hard foam body 青岛金北洋工程材料有限公司 2004-07-28 CN claimed
WO-2001066626-A1 HYBRID MIXED ION CLAY STRUCTURES FOR POLYMER NANOCOMPOSITE FORMATION MICHIGAN STATE UNIVERSITY (US) 2001-09-13 WO claimed
US-4843160-A Preparation of alpha-aminoalkylphenols THE DOW CHEMICAL COMPANY (US) 1989-06-27 US claimed
US-4654401-A SOLVENT RESISTANCE, HIGH IMPACT STRENGTH MOLDING MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-03-31 US claimed
EP-0145164-B1 PROCESS FOR IMPROVING MOISTURE RESISTANCE OR EPOXY RESINS BY ADDITION OF CHROMIUM IONS NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1987-03-04 EP claimed
US-4632962-A USING IN MAKING MODIFIED POLYESTERS, POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1986-12-30 US claimed
EP-0186060-A2 Hydroxyl group graft modified polyolefins GENERAL ELECTRIC COMPANY (US) 1986-07-02 EP claimed