SCHEMBL30962023

SCHEMBL30962023

CC(C)(C)OC(=O)N1CCN(c2cnnc(Cl)c2Cl)CC1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.48
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ SMARCA2 P51531 1/20 0.45
▸ SMARCA4 P51532 1/20 0.45
▸ PBRM1 Q86U86 1/20 0.45
▸ CKS1B P61024 2/20 0.45
▸ SKP1 P63208 2/20 0.45
▸ SKP2 Q13309 2/20 0.45
▸ MAPT P10636 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ TSHR P16473 1/20 0.44
▸ GPR119 Q8TDV5 8/20 0.43
▸ HTT P42858 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ STS P08842 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30962027 0.84 MAPT (0.45) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL30962024 0.82 POLB (0.48) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL31652116 0.82 POLB (0.54) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL1967744 0.79 POLB (0.60) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL25216918 0.78 GPR119 (0.57) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL17207602 0.78 GPR119 (0.47) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL4309116 0.78 CKS1B (0.55) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL18790713 0.78 CKS1B (0.49) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL30962028 0.78 MAPT (0.49) POLBMEN1KMT2ASMARCA2SMARCA4
SCHEMBL38663361 0.78 CKS1B (0.49) POLBMEN1KMT2ASMARCA2SMARCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638442-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS Uniquest Pty Limited (AU) 2025-10-29 — — EP disclosed
WO-2024130342-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS UNIQUEST PTY LIMITED (AU) 2024-06-27 — — WO disclosed
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