SCHEMBL30962024

SCHEMBL30962024

CC(C)(C)OC(=O)N1CCN(c2cnncc2Cl)CC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.48
▸ MEN1 O00255 4/20 0.48
▸ KMT2A Q03164 4/20 0.48
▸ CKS1B P61024 2/20 0.47
▸ SKP1 P63208 2/20 0.47
▸ SKP2 Q13309 2/20 0.47
▸ MAPT P10636 3/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ TSHR P16473 1/20 0.46
▸ GPR119 Q8TDV5 4/20 0.46
▸ SMARCA2 P51531 1/20 0.45
▸ SMARCA4 P51532 1/20 0.45
▸ PBRM1 Q86U86 1/20 0.45
▸ STS P08842 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907903 0.83 GPR119 (0.55) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL29282350 0.82 POLB (0.48) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL30962023 0.82 POLB (0.48) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL25209734 0.82 GPR119 (0.54) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL30599749 0.82 GPR119 (0.54) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL30208139 0.79 MEN1 (0.56) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL14852499 0.79 MEN1 (0.56) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL16707785 0.79 MEN1 (0.54) POLBMEN1KMT2ACKS1BSKP1
SCHEMBL17030861 0.77 MEN1 (0.46) POLBMEN1KMT2AMAPTLMNA
SCHEMBL2365793 0.77 MEN1 (0.58) POLBMEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638442-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS Uniquest Pty Limited (AU) 2025-10-29 — — EP disclosed
WO-2024130342-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS UNIQUEST PTY LIMITED (AU) 2024-06-27 — — WO disclosed
Send feedback